Structure of PDB 4mbs Chain A

Receptor sequence
>4mbsA (length=346) Species: 1501,9606 [Search protein sequence]
PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIY
LLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFF
IILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTR
SQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGIL
KTLLRMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVG
KDQFEEVEEEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLN
NCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ
3D structure
PDB4mbs Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex.
ChainA
Resolution2.71 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MRV A Y37 W86 Y89 Y108 F109 F112 F182 T195 W248 Y251 L255 E283 Y19 W68 Y71 Y90 F91 F94 F164 T177 W281 Y284 L288 E316
BS02 ZN A C1006 C1009 C1039 C1042 C211 C214 C244 C247
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0016493 C-C chemokine receptor activity
GO:0046872 metal ion binding
Biological Process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0043448 alkane catabolic process
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4mbs, PDBe:4mbs, PDBj:4mbs
PDBsum4mbs
PubMed24030490
UniProtP00268|RUBR_CLOPA Rubredoxin;
P51681

[Back to BioLiP]