Structure of PDB 4mbb Chain A

Receptor sequence
>4mbbA (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSNHIPERWKDYLPVGQRMPGTRFIAFKVPLQKSFEKKLAPEECFSP
LDLFNKIREQNEELGLIIDLTYTQRYYKPEDLPETVPYLKIFTVGHQVPD
DETIFKFKHAVNGFLKENKDNDKLIGVHSTHGLNRTGYLICRYLIDVEGV
RPDDAIELFNRCRGHCLERQNYIEDLQNGPIRKN
3D structure
PDB4mbb Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
ChainA
Resolution1.849 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CL A T94 Y95 T96 R158 T71 Y72 T73 R135
BS02 PO4 A S152 T153 H154 L156 N157 R158 S129 T130 H131 L133 N134 R135
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:4mbb, PDBe:4mbb, PDBj:4mbb
PDBsum4mbb
PubMed24447265
UniProtO75319|DUS11_HUMAN RNA/RNP complex-1-interacting phosphatase (Gene Name=DUSP11)

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