Structure of PDB 4m9e Chain A

Receptor sequence
>4m9eA (length=85) Species: 10090 (Mus musculus) [Search protein sequence]
THTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELT
RHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
3D structure
PDB4m9e Structural basis for Klf4 recognition of methylated DNA.
ChainA
Resolution1.851 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y411 K413 H416 R443 E446 R449 R471 H474 Y13 K15 H18 R45 E48 R51 R73 H76 PDBbind-CN: Kd=30nM
BS02 dna A K413 S415 Y430 S472 D473 K15 S17 Y32 S74 D75 PDBbind-CN: Kd=30nM
BS03 ZN A C462 C465 H478 H482 C64 C67 H80 H84
BS04 ZN A C432 C437 H450 H454 C34 C39 H52 H56
BS05 ZN A C402 C407 H420 H424 C4 C9 H22 H26
External links
PDB RCSB:4m9e, PDBe:4m9e, PDBj:4m9e
PDBsum4m9e
PubMed24520114
UniProtQ60793|KLF4_MOUSE Krueppel-like factor 4 (Gene Name=Klf4)

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