Structure of PDB 4m8l Chain A

Receptor sequence
>4m8lA (length=220) Species: 263 (Francisella tularensis) [Search protein sequence]
KKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKT
VVSSSEDSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGA
ALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIV
KLGGQPVYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIF
ALKPADTVIMATKDSNIVVL
3D structure
PDB4m8l crystal structure of RpiA-R5P complex
ChainA
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.1.6: ribose-5-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5RP A T34 G35 S36 T37 G88 D90 K100 G101 G102 G103 E109 K127 T30 G31 S32 T33 G84 D86 K96 G97 G98 G99 E105 K123
BS02 ARF A F204 K207 F200 K203
BS03 ARF A H95 E97 H91 E93
BS04 ARF A S36 K65 S32 K61
BS05 ARF A E189 N193 E185 N189
BS06 ARF A K67 D72 V73 K63 D68 V69
BS07 ARF A K53 F71 D72 K49 F67 D68
Gene Ontology
Molecular Function
GO:0004751 ribose-5-phosphate isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0006014 D-ribose metabolic process
GO:0006098 pentose-phosphate shunt
GO:0009052 pentose-phosphate shunt, non-oxidative branch
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4m8l, PDBe:4m8l, PDBj:4m8l
PDBsum4m8l
PubMed
UniProtA4IYN5|RPIA_FRATW Ribose-5-phosphate isomerase A (Gene Name=rpiA)

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