Structure of PDB 4m8j Chain A

Receptor sequence
>4m8jA (length=495) Species: 525369 (Proteus mirabilis ATCC 29906) [Search protein sequence]
GIEPKVFFPPLIIVGILCWLTVRDLDASNEVINAVFSYVTNVWGWAFEWY
MVIMFGGWFWLVFGRYAKKRLGDEKPEFSTASWIFMMFASCTSAAVLFWG
SIEIYYYISSPPFGMEGYSAPAKEIGLAYSLFHWGPLPWATYSFLSVAFA
YFFFVRKMEVIRPSSTLVPLVGEKHVNGLFGTVVDNFYLVALILAMGTSL
GLATPLVTECIQYLFGIPHTLQLDAIIISCWILLNAICVAFGLQKGVKIA
SDVETYLSFLMLGWVFIVGGASFIVNYFTDSVGTLLMYMPRMLFYTDPIG
KGGFPQAWTVFYWAWWVIYAIQMSIFLARISKGRTVRELCLGMVSGLTAG
TWLIWTILGGNTLQLIDQNILNIPQLIDQYGVPRAIIETWAALPLSTATM
WGFFILCFIATVTLINACSYTLAMSTCRSMKEGADPPLLVRIGWSVLVGI
IGIILLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKVHWK
3D structure
PDB4m8j Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT.
ChainA
Resolution3.294 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NM2 A W147 W323 W324 W139 W315 W316
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0022857 transmembrane transporter activity
GO:0044667 (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity
Biological Process
GO:0009437 carnitine metabolic process
GO:0071705 nitrogen compound transport
GO:1900749 (R)-carnitine transport
GO:1900751 4-(trimethylammonio)butanoate transport
GO:1902270 (R)-carnitine transmembrane transport
GO:1902603 carnitine transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4m8j, PDBe:4m8j, PDBj:4m8j
PDBsum4m8j
PubMed24101465
UniProtB4EY22|CAIT_PROMH L-carnitine/gamma-butyrobetaine antiporter (Gene Name=caiT)

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