Structure of PDB 4m7s Chain A

Receptor sequence
>4m7sA (length=214) Species: 1397 (Niallia circulans) [Search protein sequence]
MDKLFSMIEVEVNSQCNRTCWYCPNSVTGEMDPALYKTLMEQLSSLDFAG
RISFHFYGEPLLCKNLDLFVGMTTEYIPRARPIIYTNGDFLTEKRLQTLT
ELGIQKFIVTQHAGADKEKVVYLDHSASKANMSCMVPSNLAVVTVLGNVL
PCFEDFNQKMVMGNIGEQHISDIWHNDKFTSFRKMLKEGHRGKSDLCKNC
NNVSVQTEEQYDYV
3D structure
PDB4m7s X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry.
ChainA
Resolution2.022 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.99.38: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A C169 P172 C187 E189 R226 C232 C235 N237 C134 P137 C152 E154 R191 C197 C200 N202
BS02 SF4 A C16 R18 C20 C23 N25 Y62 N92 H117 C16 R18 C20 C23 N25 Y57 N87 H112
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4m7s, PDBe:4m7s, PDBj:4m7s
PDBsum4m7s
PubMed24048029
UniProtQ8G907|BTRN_NIACI S-adenosyl-L-methionine-dependent 2-deoxy-scyllo-inosamine dehydrogenase (Gene Name=btrN)

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