Structure of PDB 4m6t Chain A

Receptor sequence
>4m6tA (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
KDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCA
QVIFDSDPAPKDTSGAAALEMMSQAMIRGMMSGENLYFQSGNDLYFVKLP
NFLSVEPRPFDPQYYEDEFEEEGRTRLKLKVENTIRWRIRRDEEGNEIKE
SNARIVKWSDGSMSLHLGNEVFDVYKA
3D structure
PDB4m6t Structural insights into Paf1 complex assembly and histone binding
ChainA
Resolution2.498 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A A26 K28 I30 P41 V42 E43 V44 R169 A17 K19 I21 P32 V33 E34 V35 R154
Gene Ontology
Biological Process
GO:0006368 transcription elongation by RNA polymerase II
Cellular Component
GO:0016593 Cdc73/Paf1 complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4m6t, PDBe:4m6t, PDBj:4m6t
PDBsum4m6t
PubMed24038468
UniProtQ8N7H5;
Q8WVC0|LEO1_HUMAN RNA polymerase-associated protein LEO1 (Gene Name=LEO1)

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