Structure of PDB 4m5f Chain A

Receptor sequence
>4m5fA (length=399) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
TATSDLIESLISYSWDDWQVTRQEARRVIAAIRNDNVPDATIAALDKSGS
LIKLFQRVGPPELARSLIASIAGRTTMQRYQARNALIRSLINNPLGTQTD
NWIYFPTITFFDICADLADAAGRLGFAAAGATGVASQAIQGPFSGVGATG
VNPTDLPSIAFGDQLKLLNKDPATVTKYSNPLGDLGAYLSQLSPQDKLNQ
AQTLVGQPISTLFPDAYPGNPPSRAKVMSAAARKYDLTPQLIGAIILAEQ
RDQTRDEDAKDYQAAVSIKSANTSIGLGQVVVSTAIKYELFTDLLGQPVR
RGLSRKAVATLLASDEFNIFATARYIRYVANLASQQDLRKLPKTRGAFPS
IDLRAYAGNPRNWPRDNVRALASEYTSRPWDDNLSPGWPMFVDDAYATF
3D structure
PDB4m5f Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N181 D253 Q254 E258 Q280 N180 D252 Q253 E257 Q279
BS02 CA A E375 S378 R379 D382 N384 E374 S377 R378 D381 N383
BS03 CA A E258 D262 S275 Q280 E257 D261 S274 Q279
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0033644 host cell membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4m5f, PDBe:4m5f, PDBj:4m5f
PDBsum4m5f
PubMed24724564
UniProtQ9HYC5|TSE3_PSEAE Peptidoglycan muramidase Tse3 (Gene Name=tse3)

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