Structure of PDB 4m2j Chain A

Receptor sequence
>4m2jA (length=382) Species: 58340 (Streptomyces lavendulae subsp. lavendulae) [Search protein sequence]
SSLRPRREDPPVLEEWYRRHLGPDIHDISSSGVHPYSFAEIRDVCRIPAA
DLDAVVMDDSVSQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNA
LLHRGDRVVVQEGIYHSLGHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGL
VTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIA
HRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVGWAVAPKELLTATFPLR
DRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAHLTGWMAAHEEL
VRWTPPEGGVCALPVFRELERAAAGPQEVERFCLELLERHRTLLVPGTAF
GAPHGARLGFGGPQEDFRAGLDGLSRFLRERA
3D structure
PDB4m2j Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
ChainA
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A G90 S91 S92 Y116 N166 D194 T222 S224 K225 R233 G89 S90 S91 Y115 N165 D193 T221 S223 K224 R232
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4m2j, PDBe:4m2j, PDBj:4m2j
PDBsum4m2j
PubMed24505011
UniProtG9MBV4

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