Structure of PDB 4m25 Chain A

Receptor sequence
>4m25A (length=336) Species: 58340 (Streptomyces lavendulae subsp. lavendulae) [Search protein sequence]
TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQD
FLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLM
LYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEDA
FHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPD
ESHLPKNNTIATEEEAARFATIQRMIDERPLGPLLYGSRLDPYMRLDPYF
TSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPF
QARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG
3D structure
PDB4m25 Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.
ChainA
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.41: L-arginine hydroxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H154 E156 H303 H146 E148 H295
BS02 FE A D157 H211 D149 H203
BS03 AKG A I132 L151 H154 E156 T180 H303 R305 R317 R321 I124 L143 H146 E148 T172 H295 R297 R309 R313
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0102525 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity

View graph for
Molecular Function
External links
PDB RCSB:4m25, PDBe:4m25, PDBj:4m25
PDBsum4m25
PubMed24505011
UniProtG9MBV2

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