Structure of PDB 4lys Chain A

Receptor sequence
>4lysA (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPT
3D structure
PDB4lys 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading.
ChainA
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2SJ A W81 P82 F83 L92 N140 I146 W39 P40 F41 L50 N98 I104 PDBbind-CN: -logKd/Ki=4.34,Kd=46uM
External links
PDB RCSB:4lys, PDBe:4lys, PDBj:4lys
PDBsum4lys
PubMed24272870
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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