Structure of PDB 4lwz Chain A

Receptor sequence
>4lwzA (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVD
GKTIKAQIWDTARAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRD
HADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNV
EAAFQTILTEIY
3D structure
PDB4lwz Structural basis of myosin V Rab GTPase-dependent cargo recognition.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A G21 G23 K24 S25 N26 F36 N37 L38 S40 N124 K125 D127 L128 S154 A155 L156 G15 G17 K18 S19 N20 F30 N31 L32 S34 N113 K114 D116 L117 S143 A144 L145
BS02 MG A S25 T43 S19 T37
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4lwz, PDBe:4lwz, PDBj:4lwz
PDBsum4lwz
PubMed24248336
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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