Structure of PDB 4lr2 Chain A

Receptor sequence
>4lr2A (length=379) Species: 9606 (Homo sapiens) [Search protein sequence]
LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPN
HYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTN
QLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNN
SNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKM
LGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILP
KINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWT
IVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPM
MCHILGLKPHPNNGTFGHTKCLLVDQWCI
3D structure
PDB4lr2 Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
ChainA
Resolution1.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.29: bis(5'-adenosyl)-triphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D34 T70 D237 H238 D11 T47 D214 H215
BS02 ZN A D189 H193 H336 D166 H170 H313
External links
PDB RCSB:4lr2, PDBe:4lr2, PDBj:4lr2
PDBsum4lr2
PubMed24338010
UniProtQ9Y6X5|ENPP4_HUMAN Bis(5'-adenosyl)-triphosphatase ENPP4 (Gene Name=ENPP4)

[Back to BioLiP]