Structure of PDB 4lnq Chain A

Receptor sequence
>4lnqA (length=195) Species: 10090 (Mus musculus) [Search protein sequence]
GPHMKGAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESKYYRVKV
FNMDLKEKFTENKFITISKYFNSSGILEINETATVSEAAPNQMFEVPKNI
IRSAKETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIK
VVWDKEQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGE
3D structure
PDB4lnq Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S166 H222 R224 G226 S118 H174 R176 G178 PDBbind-CN: Kd=1.33uM
BS02 dna A K180 N182 K184 S185 T187 K132 N134 K136 S137 T139 PDBbind-CN: Kd=1.33uM
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:4lnq, PDBe:4lnq, PDBj:4lnq
PDBsum4lnq
PubMed24419611
UniProtQ9R002|IFI2_MOUSE Interferon-activable protein 202 (Gene Name=Ifi202)

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