Structure of PDB 4lma Chain A

Receptor sequence
>4lmaA (length=318) Species: 267872 (Microcystis aeruginosa PCC 7806) [Search protein sequence]
MRIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIG
THMINSAEKAGLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPET
MSLERRAMLKAYGATLELTPGSQGMKGAILRAQQIVDSIPGAYMLQQFRN
PSNPEIHRLTTAEEIWQDTEGQVDFIVAGVGTGGTITGVAEVIKSRKPSF
QVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLIDEVITVSDEE
AFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGE
RYLSTLMFQNIEERELTL
3D structure
PDB4lma Structural and biochemical analyses of Microcystis aeruginosa O-acetylserine sulfhydrylases reveal a negative feedback regulation of cysteine biosynthesis.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K46 S269
Catalytic site (residue number reindexed from 1) K46 S269
Enzyme Commision number 2.5.1.47: cysteine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A K46 N77 G181 T182 G183 T185 G225 S269 P296 K46 N77 G181 T182 G183 T185 G225 S269 P296
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lma, PDBe:4lma, PDBj:4lma
PDBsum4lma
PubMed24275508
UniProtA8YBS4

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