Structure of PDB 4lkv Chain A

Receptor sequence
>4lkvA (length=312) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
SSLLPFSYLYEKIINFRNTLYDKGFLKIKKLPVPVISVGNLSVGGSGKTS
FVMYLADLLKDKRVCILSRGYKRKSKGTLIVSEYGNLKVSWEEAGDEPYL
MAKLLPHVSVVASEDRYKGGLLALEKLSPEVFILDDGFQHRKLHRDLNIL
LLKKKDLKDRLLPAGNLREPLKEIRRADALVLTYQEVEPFEFFTGKPTFK
MFREFCCLLNSDFEEVPFDILKEREVIAFSGLGDNGQFRKVLKNLGIKVK
EFMSFPDHYDYSDFTPEEGEIYLTTPKDLIKLQGYENVFALNFKVKLERE
EKLKKLIYRIFY
3D structure
PDB4lkv Structural Basis of Lipid Binding for the Membrane-embedded Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK.
ChainA
Resolution3.5109 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.130: tetraacyldisaccharide 4'-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LP4 A Y13 R72 Y10 R69
BS02 LP5 A R72 H143 R69 H140
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0009029 tetraacyldisaccharide 4'-kinase activity
GO:0016301 kinase activity
Biological Process
GO:0009244 lipopolysaccharide core region biosynthetic process
GO:0009245 lipid A biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lkv, PDBe:4lkv, PDBj:4lkv
PDBsum4lkv
PubMed25023290
UniProtO67572|LPXK_AQUAE Tetraacyldisaccharide 4'-kinase (Gene Name=lpxK)

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