Structure of PDB 4lj5 Chain A

Receptor sequence
>4lj5A (length=320) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEVTEEDIAEIVSRWTGIPVSKLLEKLLRLEEELHKRVVGQDEAIRAVAD
AIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMIRI
DMTEYMEKHAVSRLIGAPPGGQLTEAVRRRPYSVILFDEIEKAHPDVFNI
LLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQKGWPYERIR
DEVFKVLQQHFRPEFLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAE
KRISLELTEAAKDFLAERGYDPVFGARPLRRVIQRELETPLAQKILAGEV
KEGDRVQVDVGPAGLVFAVP
3D structure
PDB4lj5 Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A R559 V561 T597 G598 V599 G600 K601 T602 I765 Q769 A805 R37 V39 T75 G76 V77 G78 K79 T80 I236 Q240 A276 PDBbind-CN: -logKd/Ki=6.29,Kd=0.51uM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:4lj5, PDBe:4lj5, PDBj:4lj5
PDBsum4lj5
PubMed24531492
UniProtQ9RA63|CLPB_THET8 Chaperone protein ClpB (Gene Name=clpB)

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