Structure of PDB 4ld0 Chain A

Receptor sequence
>4ld0A (length=158) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MVVAGIDPGITHLGLGVVAVEGALKARLLHGEVVKTSPQEPAKERVGRIH
ARVLEVLHRFRPEAVAVQEQFFYRQNELAYKVGWALGAVLVAAFEAGVPV
YAYGPMQVKQALAKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYA
RMGTAKPL
3D structure
PDB4ld0 Crystal structure of RuvC resolvase in complex with Holliday junction substrate.
ChainA
Resolution3.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.10: crossover junction endodeoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A I10 T11 P40 R47 Q72 F73 F74 L80 M108 I10 T11 P38 R45 Q70 F71 F72 L78 M106
BS02 dna A R76 R140 R74 R132
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

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Cellular Component
External links
PDB RCSB:4ld0, PDBe:4ld0, PDBj:4ld0
PDBsum4ld0
PubMed23980027
UniProtQ5SJC4|RUVC_THET8 Crossover junction endodeoxyribonuclease RuvC (Gene Name=ruvC)

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