Structure of PDB 4lcr Chain A

Receptor sequence
>4lcrA (length=485) Species: 99883 (Tetraodon nigroviridis) [Search protein sequence]
AGEILIKGGKVVNEDCSFFSDVHIRGGKIVEVGPDLRVPPGARVIDATDR
LVIPGGIDTHTHMELAFMGTRAVDDFHIGTKAALAGGTTMILDFVMTQKG
QSLLEAYDLWRKTADPKVCCDYSLHVAVTWWSDEVKDEMRTLAQERGVNS
FKMFMAYKGLFMLRDDELYAVFSHCKEVGAIAQVHAENGDLIAEGAKKML
SLGITGPEGHELCRPEAVEAEATQRAITIASAVNCPLYVVHVMSKSAADV
VSKARKDGRVVFGEPIAASLGTDGTNYWHKDWAHAAQYVMGPPLRPDPST
PGYLMDLLANDDLTLTGTDNCTFSRCQKALGKDDFTRIPNGVNGVEDRMS
VIWEKGVHSGKMDENRFVAVTSSNAAKIFNFYPQKGRIAKDSDADVVIWD
PKTTRKISAQTHHQAVDYNIFEGMECHGVPVVTVSRGRVVYEEGRLKVSP
GQGRFIHRQPFSEFVYKRIRQRDEVGKPAVVIREP
3D structure
PDB4lcr Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 URP A H65 K155 Y160 H188 M293 G294 D322 N343 G344 H62 K152 Y157 H185 M290 G291 D319 N340 G341
BS02 ZN A H63 H65 K155 D322 H60 H62 K152 D319
BS03 ZN A K155 H188 H244 K152 H185 H241
Gene Ontology
Molecular Function
GO:0004157 dihydropyrimidinase activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding
Biological Process
GO:0006208 pyrimidine nucleobase catabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4lcr, PDBe:4lcr, PDBj:4lcr
PDBsum4lcr
PubMed24005677
UniProtQ4SMR4

[Back to BioLiP]