Structure of PDB 4lby Chain A

Receptor sequence
>4lbyA (length=401) Species: 274 (Thermus thermophilus) [Search protein sequence]
FVRTKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVEVKDYGDIDKAP
EERARGITINTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGAIL
VVSAADGPMPQTREHILLARQVGVPYIVVFMNKVDMVDDPELLDLVEMEV
RDLLNQYEFPGDEVPVIRGSALLALEQMHRNPKTRRGENEWVDKIWELLD
AIDEYIPTPVRDVDKPFLMPVEDVFTITGRGTVATGRIERGKVKVGDEVE
IVGLAPETRKTVVTGVEMHRKTLQEGIAGDNVGVLLRGVSREEVERGQVL
AKPGSITPHTKFEASVYVLKKEEGGRHTGFFSGYRPQFYFRTTDVTGVVQ
LPPGVEMVMPGDNVTFTVELIKPVALEEGLRFAIREGGRTVGAGVVTKIL
E
3D structure
PDB4lby Identifying ligand-binding hot spots in proteins using brominated fragments.
ChainA
Resolution2.692 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 K24 T25 T62 H85
Catalytic site (residue number reindexed from 1) D17 K20 T21 T58 H81
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A V20 D21 G23 K24 T25 T26 Y47 I61 T62 G84 N136 K137 D139 M140 S174 L176 V16 D17 G19 K20 T21 T22 Y43 I57 T58 G80 N132 K133 D135 M136 S170 L172
BS02 MG A T25 T62 T21 T58
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lby, PDBe:4lby, PDBj:4lby
PDBsum4lby
PubMed23989163
UniProtP60338|EFTU1_THETH Elongation factor Tu-A (Gene Name=tufA)

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