Structure of PDB 4lbo Chain A

Receptor sequence
>4lboA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB4lbo Galectin-3 interactions with glycosphingolipids.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R162 E184 R186 R50 E72 R74 PDBbind-CN: -logKd/Ki=5.77,Kd=1.7uM
BS02 GAL A H158 R162 N174 W181 E184 H46 R50 N62 W69 E72 PDBbind-CN: -logKd/Ki=5.77,Kd=1.7uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:4lbo, PDBe:4lbo, PDBj:4lbo
PDBsum4lbo
PubMed24326249
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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