Structure of PDB 4lam Chain A

Receptor sequence
>4lamA (length=365) Species: 983644 (Cordyceps militaris CM01) [Search protein sequence]
TPVVVDIHTHMYPPSYIAMLEKRQTIPLVRTFPQADEPRLILLSSELAAL
DAALADPAAKLPGRPLSTHFASLAQKMHFMDTNGIRVSVISLANPWFDFL
APDEAPGIADAVNAEFSDMCAQHVGRLFFFAALPLSAPVDAVKASIERVK
NLKYCRGIILGTSGLGKGLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEV
YGPRSEEYGHVLPLALGFPMETTIAVARMYMAGVFDHVRNLQMLLAHSGG
TLPFLAGRIESCIVHDGHLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEV
GLQAAIASSGADRLMFGTNHPFFPPIWDSSRLNAQAVIKAVGEGSSDAAA
VMGLNAVRVLSLKAE
3D structure
PDB4lam Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H12 H14 H195 N323 H8 H10 H191 N319
BS02 5CU A H14 R68 N98 H195 F222 H251 N323 F326 H10 R64 N94 H191 F218 H247 N319 F322
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016831 carboxy-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0019748 secondary metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lam, PDBe:4lam, PDBj:4lam
PDBsum4lam
PubMed23917530
UniProtG3J531

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