Structure of PDB 4laa Chain A

Receptor sequence
>4laaA (length=129) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LHKEPATLIKAIDGDTVKLMYKGQPMTFRHLLVDTPEFNEKYGPEASAFT
KKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVA
YVYKGNNTHEQLLRKAEAQAKKEKLNIWS
3D structure
PDB4laa Crystal structure of Staphylococcal nuclease variant Delta+PHS L36H at cryogenic temperature
ChainA
Resolution1.58 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 R35 D40 T41 E43 R87
Catalytic site (residue number reindexed from 1) D15 R29 D34 T35 E37 R75
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 THP A R35 K84 Y85 R87 Y113 Y115 R29 K72 Y73 R75 Y101 Y103
BS02 CA A D21 D40 T41 E43 D15 D34 T35 E37
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4laa, PDBe:4laa, PDBj:4laa
PDBsum4laa
PubMed
UniProtP00644|NUC_STAAU Thermonuclease (Gene Name=nuc)

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