Structure of PDB 4l5s Chain A

Receptor sequence
>4l5sA (length=199) Species: 10090 (Mus musculus) [Search protein sequence]
STPKKNISKGAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESKYY
RVKVFNMDLKEKFTENQFITISKYFNSSGILEINETATVSEAAPNQMFEV
PKNIIRSAKETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNE
DNIKVVWDKEQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGE
3D structure
PDB4l5s Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation.
ChainA
Resolution2.94 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K180 N182 D183 K184 S185 K198 K136 N138 D139 K140 S141 K154
BS02 dna A T46 P47 K48 T2 P3 K4
BS03 dna A S166 H222 R224 G226 N227 N236 S122 H178 R180 G182 N183 N192
BS04 dna A K104 E105 K60 E61
BS05 dna A F73 N74 N207 F239 I240 K241 F29 N30 N163 F195 I196 K197
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:4l5s, PDBe:4l5s, PDBj:4l5s
PDBsum4l5s
PubMed23850291
UniProtQ9R002|IFI2_MOUSE Interferon-activable protein 202 (Gene Name=Ifi202)

[Back to BioLiP]