Structure of PDB 4l5j Chain A

Receptor sequence
>4l5jA (length=308) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
EQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGI
IRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHM
LMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTG
IGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVG
IGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNI
KIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQD
TAAAILRS
3D structure
PDB4l5j Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition.
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HSX A F124 G125 E126 A127 G209 T220 D243 L245 K288 F115 G116 E117 A118 G200 T211 D234 L236 K279 PDBbind-CN: -logKd/Ki=3.00,Kd~1mM
Gene Ontology
Molecular Function
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0030246 carbohydrate binding
GO:0042802 identical protein binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0009408 response to heat
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4l5j, PDBe:4l5j, PDBj:4l5j
PDBsum4l5j
PubMed24047255
UniProtP76141|LSRR_ECOLI Transcriptional regulator LsrR (Gene Name=lsrR)

[Back to BioLiP]