Structure of PDB 4l4j Chain A

Receptor sequence
>4l4jA (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
ASSVFLFPPKPKDTLMISRTPEVTCVVVDVSAEDPEVQFNWYVDGVEVHN
AKTKPREEQFNSTFRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTI
SKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQ
PENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHY
TQKSLSLS
3D structure
PDB4l4j An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA A F241 F243 F5 F7
External links
PDB RCSB:4l4j, PDBe:4l4j, PDBj:4l4j
PDBsum4l4j
PubMed23872058
UniProtP01859|IGHG2_HUMAN Immunoglobulin heavy constant gamma 2 (Gene Name=IGHG2)

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