Structure of PDB 4l3c Chain A

Receptor sequence
>4l3cA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB4l3c Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
ChainA
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 K66 V67 H70 T73 H74 D77 Y84 R97 Y99 T143 K146 W147 Y159 T163 W167 Y171 Y7 E63 K66 V67 H70 T73 H74 D77 Y84 R97 Y99 T143 K146 W147 Y159 T163 W167 Y171
BS02 peptide A H191 A193 S195 E198 E254 W274 E275 P276 H191 A193 S195 E198 E254 W274 E275 P276
External links
PDB RCSB:4l3c, PDBe:4l3c, PDBj:4l3c
PDBsum4l3c
PubMed24338476
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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