Structure of PDB 4l0y Chain A

Receptor sequence
>4l0yA (length=128) Species: 10090 (Mus musculus) [Search protein sequence]
SMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPD
GTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLT
ITVFTNPPQVATYHRAIKITVDGPREPR
3D structure
PDB4l0y Structural basis of Ets1 activation by Runx1.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R142 K167 T169 V170 D171 R93 K118 T120 V121 D122 PDBbind-CN: Kd=3.1nM
BS02 dna A R80 K83 R135 R142 R174 R177 R31 K34 R86 R93 R125 R128 PDBbind-CN: Kd=3.1nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4l0y, PDBe:4l0y, PDBj:4l0y
PDBsum4l0y
PubMed24646888
UniProtQ03347|RUNX1_MOUSE Runt-related transcription factor 1 (Gene Name=Runx1)

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