Structure of PDB 4kv4 Chain A

Receptor sequence
>4kv4A (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
AGSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKMPD
3D structure
PDB4kv4 Brd4 maintains constitutively active NF-kappa B in cancer cells by binding to acetylated RelA.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W29 V35 N88 H92 W26 V32 N85 H89
External links
PDB RCSB:4kv4, PDBe:4kv4, PDBj:4kv4
PDBsum4kv4
PubMed23686307
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

[Back to BioLiP]