Structure of PDB 4kr7 Chain A

Receptor sequence
>4kr7A (length=386) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPID
ENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRT
FKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVR
PEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIE
SVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKK
RVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWS
IESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNP
ATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE
3D structure
PDB4kr7 Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
ChainA
Resolution3.421 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.4: tRNA uracil 4-sulfurtransferase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0016783 sulfurtransferase activity
GO:0140741 tRNA-uracil-4 sulfurtransferase activity
Biological Process
GO:0002937 tRNA 4-thiouridine biosynthesis
GO:0009228 thiamine biosynthetic process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0034227 tRNA thio-modification
GO:0052837 thiazole biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4kr7, PDBe:4kr7, PDBj:4kr7
PDBsum4kr7
PubMed24705700
UniProtQ9X220|THII_THEMA Probable tRNA sulfurtransferase (Gene Name=thiI)

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