Structure of PDB 4kp4 Chain A

Receptor sequence
>4kp4A (length=219) Species: 83333,243274 [Search protein sequence]
ADDRTLLMAGVSHDLRTPLTRIRAYAETIYNSLGELDLSTLKELAESINK
DIEECNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETA
LYPGSIEVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVE
DDGPGIAPEQRKHLFQPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLEL
GTSERGGLSIRAWLPVPVT
3D structure
PDB4kp4 Visualizing autophosphorylation in histidine kinases.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A H243 N1347 R1350 Y1351 D1373 I1378 R1392 G1393 A1396 G1401 T1402 G1403 L1404 G1405 L1406 L1430 H13 N125 R128 Y129 D151 I156 R170 G171 A174 G179 T180 G181 L182 G183 L184 L208 PDBbind-CN: -logKd/Ki=5.17,Kd=6.8uM
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4kp4, PDBe:4kp4, PDBj:4kp4
PDBsum4kp4
PubMed24500224
UniProtP0AEJ4|ENVZ_ECOLI Sensor histidine kinase EnvZ (Gene Name=envZ);
Q9WZV7

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