Structure of PDB 4kn1 Chain A

Receptor sequence
>4kn1A (length=205) Species: 9606 (Homo sapiens) [Search protein sequence]
RTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTS
RLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRKERF
LDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFE
SYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFY
AAAMH
3D structure
PDB4kn1 Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
ChainA
Resolution2.301 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 04J A Y76 Y101 W118 H151 R152 G153 W154 W156 W187 S190 Y53 Y78 W95 H128 R129 G130 W131 W133 W164 S167 MOAD: Kd=144nM
PDBbind-CN: -logKd/Ki=6.84,Kd=144nM
External links
PDB RCSB:4kn1, PDBe:4kn1, PDBj:4kn1
PDBsum4kn1
PubMed23934049
UniProtP14207|FOLR2_HUMAN Folate receptor beta (Gene Name=FOLR2)

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