Structure of PDB 4kmz Chain A

Receptor sequence
>4kmzA (length=203) Species: 9606 (Homo sapiens) [Search protein sequence]
TDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTSR
LYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRKERFL
DVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFES
YFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYA
AAM
3D structure
PDB4kmz Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FOL A D97 Y101 W118 R119 W150 H151 R152 G153 W154 W156 W187 S190 Y191 D73 Y77 W94 R95 W126 H127 R128 G129 W130 W132 W163 S166 Y167 MOAD: Kd=2.7nM
PDBbind-CN: -logKd/Ki=8.57,Kd=2.7nM
External links
PDB RCSB:4kmz, PDBe:4kmz, PDBj:4kmz
PDBsum4kmz
PubMed23934049
UniProtP14207|FOLR2_HUMAN Folate receptor beta (Gene Name=FOLR2)

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