Structure of PDB 4kmd Chain A

Receptor sequence
>4kmdA (length=367) Species: 9606 (Homo sapiens) [Search protein sequence]
SLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNV
GSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRE
TGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHM
LLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVP
IAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDD
LELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAIT
FVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLKLPKEYS
WPEKKLKVSILPDVVFD
3D structure
PDB4kmd Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y147 T154 F155 G158 D159 H160 V161 S162 N265 L266 S267 G268 V269 S270 E376 K398 Y120 T127 F128 G131 D132 H133 V134 S135 N238 L239 S240 G241 V242 S243 E269 K291
Gene Ontology
Molecular Function
GO:0008134 transcription factor binding

View graph for
Molecular Function
External links
PDB RCSB:4kmd, PDBe:4kmd, PDBj:4kmd
PDBsum4kmd
PubMed24217340
UniProtQ9UMX1|SUFU_HUMAN Suppressor of fused homolog (Gene Name=SUFU)

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