Structure of PDB 4kac Chain A

Receptor sequence
>4kacA (length=292) Species: 1831 (Rhodococcus sp. (in: high G+C Gram-positive bacteria)) [Search protein sequence]
EIGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNII
PHVAPSHRCIAPDLIGMGKSDKPDLDYFFDDHVRYLDAFIEALGLEEVVL
VIHDWGSALGFHWAKRNPERVKGIACMEFIRPIPTWDEWPEFARETFQAF
RTADVGRELIIDQNAFIEGALPMGVVRPLTEVEMDHYREPFLKPVDREPL
WRFPNELPIAGEPANIVALVEAYMNWLHQSPVPKLLFWGTPGVLIPPAEA
ARLAESLPNCKTVDIGPGLFLLQEDNPDLIGSEIARWLPGLA
3D structure
PDB4kac Northeast Structural Genomics Consortium Target OR150
ChainA
Resolution2.223 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N52 D117 W118 E141 W152 G255 F283
Catalytic site (residue number reindexed from 1) N39 D104 W105 E128 W139 G242 F270
Enzyme Commision number 3.8.1.5: haloalkane dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1Q9 A D117 W118 W152 F160 F179 A183 G187 P217 V256 F283 D104 W105 W139 F147 F166 A170 G174 P204 V243 F270
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018786 haloalkane dehalogenase activity
Biological Process
GO:0009636 response to toxic substance

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Molecular Function
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Biological Process
External links
PDB RCSB:4kac, PDBe:4kac, PDBj:4kac
PDBsum4kac
PubMed
UniProtP0A3G3|DHAA_RHOSO Haloalkane dehalogenase (Gene Name=dhaA)

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