Structure of PDB 4ka8 Chain A

Receptor sequence
>4ka8A (length=695) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SDETLSSNPLLQDFDFPPFDSVDASHVRPGIRALLQHLEAELEELEKSVE
PTWPKLVEPLEKIVDRLTVVWGMINHLKAVKDTPELRAAIEDVQPEKVKF
QLRLGQSKPIYNAFKAIRESPDWSSLSEARQRLVEAQIKEAVLIGIALDD
EKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSALG
LFAQAAVSKGHENATAENGPWIITLDAPSYLPVMQHAKNRALREEVYRAY
LSRASSGDLDNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMATVEKAA
ELLEKLRSASWDAAVQDMEDLKSFAKNQGAAESDSMTHWDTTFWSERLRE
SKYDINEEELRPYFSLPKVMDGLFSLAKTLFGIDIEPADGLAPVWNNDVR
FYRVKDSSGNPIAYFYFDPYSRPSEKRGGAWMDEVVSRSRVMAQKGSSVR
LPVAHMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKQDEGLVA
GIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYETGETLPEEVYKKLLA
ARTFRAGSFSLRQLKFASVDLELHTKYVPGGPESIYDVDQRVSVKTQVIP
PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFEDAGLDDIKA
VKETGQRFRNTILALGGGKAPLKVFVEFRGREPSPEPLLRHNGLL
3D structure
PDB4ka8 Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H571 E572 H575 E601 Y716
Catalytic site (residue number reindexed from 1) H481 E482 H485 E511 Y626
Enzyme Commision number 3.4.24.70: oligopeptidase A.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H571 H575 E601 H481 H485 E511
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009536 plastid
GO:0009570 chloroplast stroma

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ka8, PDBe:4ka8, PDBj:4ka8
PDBsum4ka8
PubMed24043784
UniProtQ94AM1|OOPDA_ARATH Organellar oligopeptidase A, chloroplastic/mitochondrial (Gene Name=OOP)

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