Structure of PDB 4k93 Chain A

Receptor sequence

>4k93A (length=330) Species: 347834 (Rhizobium etli CFN 42)

MTRFDVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRM
GPALEASGGSAGNTAAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGVH
YQTKPKGAFPPTARSMIFVTEDGERSMNTYLGACVELGPEDVEADVVADA
KVTYFEGYLWDPPRAKEAILDCARIAHQHGREMSMTLSDSFCVDRYRGEF
LDLMRSGKVDIVFANRQEALSLYQTDDFEEALNRIAADCKIAAVTMSENG
AVILKGRERYYVNAIRIREVVDTTGAGDLFASGFLYGYTQGRSLEDCGKL
GCLAAGIVIQQIGPRPMTSLSEAAKQAGLI

3D structure

• PDB: 4k93 CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE
• Chain: A
• Resolution: 1.5 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): R123 G273 A274 G275 D276
• Catalytic site (residue number reindexed from 1): R125 G275 A276 G277 D278

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADN	A	N9 I11 D13 M33 G56 G57 S58 N61 M125 T127 E154 Y156 T272 D276 P312	N11 I13 D15 M35 G58 G59 S60 N63 M127 T129 E156 Y158 T274 D278 P314
BS02	1Q8	A	S188 F189 D192 L218 S219 D224	S190 F191 D194 L220 S221 D226
BS03	1Q8	A	R195 Q222 R232	R197 Q224 R234
BS04	1Q8	A	L35 I36 L129 D159	L37 I38 L131 D161
BS05	1Q8	A	Q83 D86	Q85 D88
BS06	1Q8	A	Y45 R112	Y47 R114

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016301 kinase activity
• GO:0016772 transferase activity, transferring phosphorus-containing groups

Biological Process

• GO:0016310 phosphorylation

External links

• PDB: RCSB:4k93, PDBe:4k93, PDBj:4k93
• PDBsum: 4k93
• UniProt: Q2KDX6