Structure of PDB 4k8o Chain A

Receptor sequence
>4k8oA (length=254) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GSLAPLNMKGLVKFQDVSFAYPNHPNVQVLQGLTFTLYPGKVTALVGPNG
SGKSTVAALLQNLYQPTGGKVLLDGEPLVQYDHHYLHTQVAAVGQEPLLF
GRSFRENIAYGLTRTPTMEEITAVAMESGAHDFISGFPQGYDTEVGETGN
QLSGGQRQAVALARALIRKPRLLILDNATSALAAGNQLRVQRLLYESPEW
ASRTVLLITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGGCYRSMVE
ALAA
3D structure
PDB4k8o Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
ChainA
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.4.2.14: ABC-type antigen peptide transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A Y489 V497 N517 G518 S519 G520 K521 S522 T523 Q678 Y21 V29 N49 G50 S51 G52 K53 S54 T55 Q210 PDBbind-CN: -logKd/Ki=3.77,Kd=170uM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:4k8o, PDBe:4k8o, PDBj:4k8o
PDBsum4k8o
PubMed25377891
UniProtP36370|TAP1_RAT Antigen peptide transporter 1 (Gene Name=Tap1)

[Back to BioLiP]