Structure of PDB 4k66 Chain A

Receptor sequence
>4k66A (length=321) Species: 400788 (Influenza A virus (A/Indonesia/5/2005(H5N1))) [Search protein sequence]
QDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKP
LILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKANPTNDLCYPGSFNDYE
ELKYLLSRINHFEKIQIIPKSSWSDHEASSGVSSACPYLGSPSFFRNVVW
LIKKNSAYPTIKKSYNNTNQEDLLVLWGIHHPNDAAEQTRLYQNPTTYIS
IGTSTLNQRLVPKIATRSKVNGLSSRMEFFWTILKPNDAINFESNGNFIA
PEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTI
GECPKYVKSNRLVLATGLRNS
3D structure
PDB4k66 An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.
ChainA
Resolution3.005 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA A Y95 V135 S136 S137 W153 H183 E190 R193 Y92 V132 S133 S134 W150 H180 E187 R190 PDBbind-CN: -logKd/Ki=3.26,Kd=554uM
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4k66, PDBe:4k66, PDBj:4k66
PDBsum4k66
PubMed23641058
UniProtA8HWY8

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