Structure of PDB 4k37 Chain A

Receptor sequence

>4k37A (length=364) Species: 195103 (Clostridium perfringens ATCC 13124) [Search protein sequence]

PLSLLIKPASSGCNLKCTYCFYHSLSVKSYGIMRDEVLESMVKRVLNEAN
GHCSFAFQGGEPTLAGLEFFEKLMELQRKHNYKNLKIYNSLQTNGTLIDE
SWAKFLSENKFLVGLSMDGPKEIHNLNRKDCCGLDTFSKVERAAELFKKY
KVEFNILCVVTSNTARHVNKVYKYFKEKDFKFLQFINCLDPLYEEKGKYN
YSLKPKDYTKFLKNLFDFWYEDFLNGNRVSIRYFDGLLETILLGKSSSCG
MNGTCTCQFVVESDGSVYPCDFYVLDKWRLGNIQDMTMKELFETNKNHEF
IKLSFKVHEECKKCKWFRLCKGGCRRCRDSKEDSALELNYYCQSYKEFFE
YAFPRLINVANNIK

3D structure

PDB

4k37 X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.

Chain

Resolution

1.62 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.8.98.7: cysteine-type anaerobic sulfatase-maturating enzyme.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SF4	A	C255 G256 C261 T262 Q264 C276 F278 C330 R331 R332	C249 G250 C255 T256 Q258 C270 F272 C324 R325 R326
BS02	SF4	A	C317 C320 F323 C326 L344 C348 K352	C311 C314 F317 C320 L338 C342 K346
BS03	SF4	A	C15 L17 C19 C22 H25 G66 N100 R134	C13 L15 C17 C20 H23 G60 N94 R128
BS04	SAM	A	Y21 F23 Y24 G65 G66 E67 Q98 T99 S122 R134 V165 I192 C194 L195	Y19 F21 Y22 G59 G60 E61 Q92 T93 S116 R128 V159 I186 C188 L189

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:4k37, PDBe:4k37, PDBj:4k37
PDBsum	4k37
PubMed	23650368
UniProt	Q0TTH1\|ANSME_CLOP1 Cysteine-type anaerobic sulfatase-maturating enzyme (Gene Name=CPF_0616)

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