Structure of PDB 4k2m Chain A

Receptor sequence
>4k2mA (length=442) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
AGMQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEK
IDIEHDLFNYQKNREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFT
SGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPA
NSFSATENAVLASGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHL
YGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITTLSFNPYKN
FGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNL
QAAIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVW
HLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGL
QLVHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIG
3D structure
PDB4k2m The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases.
ChainA
Resolution1.71 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F151 D222 Q225 N244 K247 K284 K294
Catalytic site (residue number reindexed from 1) F153 D224 Q227 N246 K249 K286 K296
Enzyme Commision number 2.6.1.104: 3-dehydro-glucose-6-phosphate--glutamate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 O1G A G125 T126 F151 A153 D222 C224 Q225 S242 N244 Y246 K247 Y379 G127 T128 F153 A155 D224 C226 Q227 S244 N246 Y248 K249 Y381
BS02 O1G A T98 S99 Y274 K282 N292 T100 S101 Y276 K284 N294
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4k2m, PDBe:4k2m, PDBj:4k2m
PDBsum4k2m
PubMed24097983
UniProtO07566|NTDA_BACSU 3-oxo-glucose-6-phosphate:glutamate aminotransferase (Gene Name=ntdA)

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