Structure of PDB 4k25 Chain A

Receptor sequence
>4k25A (length=355) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
YKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSTKAHIHHQARI
GPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPL
IGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEIL
CDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMN
MLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIIN
KLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNF
YYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDG
WRTDQ
3D structure
PDB4k25 Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.
ChainA
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H145 D361 H105 D310
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0008252 nucleotidase activity
GO:0008270 zinc ion binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process
GO:0072670 mitochondrial tRNA threonylcarbamoyladenosine modification
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4k25, PDBe:4k25, PDBj:4k25
PDBsum4k25
PubMed23620299
UniProtP43122|QRI7_YEAST tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (Gene Name=QRI7)

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