Structure of PDB 4jyz Chain A

Receptor sequence
>4jyzA (length=542) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
PTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQD
YKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQL
HAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLAL
FEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWC
IYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQY
EFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASI
REFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENY
QGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLG
KEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVI
HWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPS
LKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTW
3D structure
PDB4jyz Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E34 R260 K270
Catalytic site (residue number reindexed from 1) E28 R254 K264
Enzyme Commision number 6.1.1.18: glutamine--tRNA ligase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004819 glutamine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0006425 glutaminyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jyz, PDBe:4jyz, PDBj:4jyz
PDBsum4jyz
PubMed23727144
UniProtP00962|SYQ_ECOLI Glutamine--tRNA ligase (Gene Name=glnS)

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