Structure of PDB 4jxt Chain A

Receptor sequence
>4jxtA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKA
KPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCK
KHLGRVLSIWEERSVYENDVLEQLKQALYG
3D structure
PDB4jxt RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N18 S19 Q20 V23 Y61 N64 D65 Q68 I110 R114 G131 N17 S18 Q19 V22 Y60 N63 D64 Q67 I109 R113 G130
Gene Ontology
Molecular Function
GO:0099122 RNA polymerase II C-terminal domain binding

View graph for
Molecular Function
External links
PDB RCSB:4jxt, PDBe:4jxt, PDBj:4jxt
PDBsum4jxt
PubMed24997600
UniProtQ96P16|RPR1A_HUMAN Regulation of nuclear pre-mRNA domain-containing protein 1A (Gene Name=RPRD1A)

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