Structure of PDB 4jwy Chain A

Receptor sequence
>4jwyA (length=269) Species: 10116 (Rattus norvegicus) [Search protein sequence]
QHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNEKRCCKGFCIDI
LKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLT
INEERSEIVDFSVPFVETGISVMVARGTTVSGLSDRKFQRPQEQYPPLKF
GTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDA
AVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQF
LGDDEIEMLERLWLSGICH
3D structure
PDB4jwy Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1N4 A H88 S114 T116 R121 G172 S173 T174 Y214 H72 S98 T100 R105 G156 S157 T158 Y198
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4jwy, PDBe:4jwy, PDBj:4jwy
PDBsum4jwy
PubMed23625947
UniProtQ62645|NMDE4_RAT Glutamate receptor ionotropic, NMDA 2D (Gene Name=Grin2d)

[Back to BioLiP]