Structure of PDB 4jwx Chain A

Receptor sequence
>4jwxA (length=280) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVK
KCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQ
RAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQR
PHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKT
GKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWK
RQIDLALLQFVGDGEMEELETLWLTGICHA
3D structure
PDB4jwx Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1N4 A H88 S114 T116 R121 G172 S173 T174 Y214 H82 S108 T110 R115 G166 S167 T168 Y208
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4jwx, PDBe:4jwx, PDBj:4jwx
PDBsum4jwx
PubMed23625947
UniProtQ00959|NMDE1_RAT Glutamate receptor ionotropic, NMDA 2A (Gene Name=Grin2a)

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