Structure of PDB 4jva Chain A

Receptor sequence
>4jvaA (length=264) Species: 10116 (Rattus norvegicus) [Search protein sequence]
AESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEG
EHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMY
NTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLK
SLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRK
GKAVEIARCLRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLL
GPCMEIMKRNIATY
3D structure
PDB4jva Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1OR A F219 E221 L222 A223 R230 A231 Q377 R381 F93 E95 L96 A97 R104 A105 Q244 R248
BS02 1OR A I302 I339 F348 G349 E350 L351 A352 R359 A360 A361 T396 Y397 I176 I206 F215 G216 E217 L218 A219 R226 A227 A228 T263 Y264
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jva, PDBe:4jva, PDBj:4jva
PDBsum4jva
PubMed23978166
UniProtP12369|KAP3_RAT cAMP-dependent protein kinase type II-beta regulatory subunit (Gene Name=Prkar2b)

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