Structure of PDB 4jv4 Chain A

Receptor sequence
>4jv4A (length=261) Species: 9913 (Bos taurus) [Search protein sequence]
DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSF
IAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYG
TPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILES
LDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRFVE
VGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSD
ILKRNIQQYNS
3D structure
PDB4jv4 Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs.
ChainA
Resolution2.952 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1OR A G199 E200 L201 A202 R209 A210 D258 W260 G93 E94 L95 A96 R103 A104 D152 W154
BS02 1OR A V313 F322 G323 E324 I325 A326 R333 A334 A335 Y371 V201 F210 G211 E212 I213 A214 R221 A222 A223 Y259
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jv4, PDBe:4jv4, PDBj:4jv4
PDBsum4jv4
PubMed23978166
UniProtP00514|KAP0_BOVIN cAMP-dependent protein kinase type I-alpha regulatory subunit (Gene Name=PRKAR1A)

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