Structure of PDB 4juh Chain A

Receptor sequence
>4juhA (length=324) Species: 59375 (Influenza A virus (A/South Carolina/1/1918(H1N1))) [Search protein sequence]
DTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCKLKGIAPL
QLGKCNIAGWLLGNPECDLLLTASSWSYIVETSNSENGTCYPGDFIDYEE
LREQLSSVSSFEKFEIFPKTSSWPNHETTKGVTAACSYAGASSFYRNLLW
LTKKGSSYPKLSKSYVNNKGKEVLVLWGVHHPPTGTDQQSLYQNADAYVS
VGSSKYNRRFTPEIAARPKVRGQAGRMNYYWTLLEPGDTITFEATGNLIA
PWYAFALNRGSGSGIITSDAPVHDCNTKCQTPHGAINSSLPFQNIHPVTI
GECPKYVRSTKLRMATGLRNIPAR
3D structure
PDB4juh Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
ChainA
Resolution2.805 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A Y95 V135 T136 H183 L194 Q226 Y91 V132 T133 H180 L191 Q223
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4juh, PDBe:4juh, PDBj:4juh
PDBsum4juh
PubMed23514882
UniProtQ9WFX3|HEMA_I18A0 Hemagglutinin (Gene Name=HA)

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