Structure of PDB 4jrp Chain A

Receptor sequence
>4jrpA (length=460) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
QQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIGEPEVFYCKPADD
YLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGYNNVR
FDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPE
NDDGLPSFRLEHLTKANGIEHDAMADVYATIAMAKLVKTRQPRLFDYLFT
HRNKHKLMALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVI
MVDLAGDISPLLELDSDTLRERLYTAKTDLGDNAAVPVKLVHINKCPVLA
QANTLRPEDADRLGINRQHCLDNLKILRENPQVREKVVAIFAEASDNVDA
QLYNGFFSDADRAAMKIVLETEPRNLPALDITFVDKRIEKLLFNYRARNF
PGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQMLVQQYADDKEKVALLK
ALWQYAEEIV
3D structure
PDB4jrp Crystal structures of Escherichia coli exonuclease I in complex with single-stranded DNA provide insights into the mechanism of processive digestion.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.11.1: exodeoxyribonuclease I.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0046872 metal ion binding
GO:0051575 5'-deoxyribose-5-phosphate lyase activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006308 DNA catabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4jrp, PDBe:4jrp, PDBj:4jrp
PDBsum4jrp
PubMed23609540
UniProtP04995|EX1_ECOLI Exodeoxyribonuclease I (Gene Name=sbcB)

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